Xeloda (capecitabine) 500 mg, 120 tablets, India, generic Order Xeloda (capecitabine) 500 mg, 120 tablets, India, generic. Medicine delivery from Europe within 4-5 days with storage conditions maintained. Payment on delivery. Order at +380996042415 via Viber or WhatsApp.

Interchangeable drugs with the same active ingredient:

Capecard

Apsibin

Capetero

Capecibex 150

Capecibex 500

Capecitabine

Caponco

Xeloda

Newcapibine

Citin

Ental-Health

Indications:

Breast cancer:

• local advanced or metastatic breast cancer, in combination with docetaxel after ineffective chemotherapy, including anthracycline drugs;
• local advanced or metastatic breast cancer, as monotherapy when chemotherapy, including taxanes and anthracycline drugs, is ineffective, or in the presence of a contraindication to therapy anthracyclines.

Colon cancer, colorectal cancer:

• colon cancer, in adjuvant therapy after surgical treatment of stage III cancer (Duke stage C)
• metastatic colorectal cancer.

Cancer stomach:

a drug for the first line of treatment of advanced gastric cancer, in combination with platinum-based drugs.

Contraindications . A history of severe, including unexpected reactions to treatment with fluoropyrimidines. Hypersensitivity to capecitabine or to any component of the drug, or fluorouracil. Known deficiency of dihydropyrimidine dehydrogenase. Pregnancy and breastfeeding. Severe leukopenia, neutropenia, thrombocytopenia. Severe liver dysfunction.Severe renal failure (creatinine clearance Concomitant use of sorivudine or its structural analogs such as brivudine.Contraindications to the use of any drug drugs used in combination.

Method of administration and dosage.

The drug Xeloda®can only be prescribed by a qualified physician experienced in the use of antineoplastic drugs. Careful monitoring is recommended for all patients during the first cycle treatment.

Treatment should be discontinued if the disease progresses or unacceptable toxicity develops.

The drug is taken orally, no later than 30 minutes after meals, with water.

monotherapy

Colon cancer, colorectal cancer and breast cancer glands the recommended daily dose of Xeloda® as adjuvant therapy is 2500 mg/m2 body surface and is used in three-week cycles: take daily for 2 weeks, after which take a week break. The total daily dose of Xeloda® is divided into two doses (1250 mg/m2 body surface in the morning and evening). The recommended total duration of adjuvant therapy in patients with stage III colon cancer is 6 months.

combination therapy

Breast cancer in combination with docetaxel, the recommended dose for the treatment of metastatic breast cancer is 1250 mg/m2 2 times a day for 2 weeks followed by a break (in combination with docetaxel 75 mg/m2 1 time every 3 weeks as an infusion).Premedication with oral corticosteroids, such as dexamethasone, is carried out before docetaxel is administered in accordance with the instructions for use docetaxel in patients receiving a combination of capecitabine plus docetaxel.

Colon cancer, colorectal cancer, stomach cancer: in the combination treatment regimen, the initial dose of Xeloda® must be reduced to 800-1000 mg / m2 2 times a day for 2 weeks followed by a week break or up to 625 mg/m2 2 times a day with continuous use. When combining irinotecan (200 mg/m2on day 1), the recommended dose is 800 mg/m22 times a day for 2 weeks, followed by a week break. The inclusion of bevacizumab in the combination regimen does not affect the initial dose of Xeloda® .

Antiemetics and premedication to ensure adequate hydration are prescribed to patients receiving Xeloda® in combination with cisplatin or oxaliplatin before administration cisplatin in accordance with the instructions for the use of cisplatin and oxaliplatin.The total recommended duration of adjuvant therapy in patients with stage III colon cancer is 6 months.

The dose of Xeloda® is calculated per body surface area. Tables 1, 2 show calculations of the standard and reduced dose (see “Dose adjustment during treatment”) for the initial dose of Xeloda® 1250 mg/m2or 1000 mg/m2 .